A bioenergetics systems evaluation of ketogenic diet liver effects > 2017

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A bioenergetics systems evaluation of ketogenic diet liver effects

채식영양

17-01-01 00:00 | 조회 0 | 댓글 0

https://pubmed.ncbi.nlm.nih.gov/28514599/[0]

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LJ. Hutfles, HM. Wilkins, SJ. Koppel, IW. Weidling, JE. Selfridge, E. Tan, JP. Thyfault, C. Slawson, AW. Fenton, H. Zhu, et al. (2017). A bioenergetics systems evaluation of ketogenic diet liver effects. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 42(9), 955-962. https://doi.org/10.1139/apnm-2017-0068

PubMed 28514599

[Abstract]
Ketogenic diets induce hepatocyte fatty acid oxidation and ketone body production. To further evaluate how ketogenic diets affect hepatocyte bioenergetic infrastructure, we analyzed livers from C57Bl/6J male mice maintained for 1 month on a ketogenic or standard chow diet. Compared with the standard diet, the ketogenic diet increased cytosolic and mitochondrial protein acetylation and also altered protein succinylation patterns. SIRT3 protein decreased while SIRT5 protein increased, and gluconeogenesis, oxidative phosphorylation, and mitochondrial biogenesis pathway proteins were variably and likely strategically altered. The pattern of changes observed can be used to inform a broader systems overview of how ketogenic diets affect liver bioenergetics.

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2017 목록
번호	제목	글쓴이	날짜	조회
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111	텍스트 Effects of Ketogenic Diets on Cardiovascular Risk Factors: E… 링크	채식영양	01-01	0
110	텍스트 Efficacy and safety of very-low-calorie ketogenic diet: a do… 링크	채식영양	01-01	1
109	텍스트 Protein-Losing Enteropathy as a Complication of the Ketogeni… 링크	채식영양	01-01	0
108	텍스트 Ketogenic Diet Compromises Both Cancellous and Cortical Bone… 링크	채식영양	01-01	0
107	텍스트 Nutritional Ketosis Affects Metabolism and Behavior in Sprag… 링크	채식영양	01-01	0
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