M. Bodenant, C. Moreau, C. Sejourné, S. Auvin, A. Delval, JM. Cuisset, P. Derambure, A. Destée, et al. (2008). [Interest of the ketogenic diet in a refractory status epilepticus in adults]. Revue neurologique, 164(2), 194-9. https://doi.org/10.1016/j.neurol.2007.08.009

PubMed 18358881

[Abstract]
INTRODUCTION: Ketogenic diets have been employed for the treatment of intractable epilepsy in children since 1921, although underlying mechanism remains unknown.

OBSERVATION: We report the case of a 54-year-old man with partial refractory status epilepticus who exhibited a favourable outcome about seven days after introduction of a ketogenic diet in association with antiepileptic drugs.

DISCUSSION: Although its efficiency was largely demonstrated in children, little is known about the impact of a ketogenic diet in adults with refractory epilepsy.

CONCLUSION: Introduction of a ketogenic diet requires a multidisciplinary approach. Its usefulness in adult intractable epilepsy and/or refractory status epilepticus merits further study into its efficacy in reducing the frequency of seizures and a possible prolonged effect.