Initial effect of injury on ketone bodies and other blood metabolites
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R. Smith, DJ. Fuller, JH. Wedge, DH. Williamson and KG. Alberti (1975). Initial effect of injury on ketone bodies and other blood metabolites. Lancet (London, England), 1(7897), 1-3. https://doi.org/10.1016/s0140-6736(75)92369-7
[Abstract]
The arterial and venous concentrations of ketone bodies and other metabolites were measured in twelve adults, from 2 to 24 hours after injury. Two groups could be distinguished, with or without hyperketonaemia (defined as more than 0.2 mmol per litre) in the 2-hour blood-sample. In the hyperdetonaemic group the concentrations of alanine, pyruvate, and lactate and the urinary nitrogen excretion were lower throughout the first 24 hours than in the non-hyperdetonaemic group. These preliminary results indicate that hyperketonaemia after trauma is associated with decreased protein breakdown.
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