Rat acetoacetate decarboxylase: its role in the disposal of 4C-ketone bodies by the fetus > 1920-1999

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Rat acetoacetate decarboxylase: its role in the disposal of 4C-ketone …

작성자 채식영양
작성일 86-01-01 00:00 | 조회 0 | 댓글 0

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FJ. López-Soriano and JM. Argilés (1986). Rat acetoacetate decarboxylase: its role in the disposal of 4C-ketone bodies by the fetus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 18(7), 446-9. https://doi.org/10.1055/s-2007-1012342

PubMed 3744292


[Abstract]
21-day pregnant rats show high tissular and plasmatic acetone concentrations when submitted to a 48-hr fast. This rise is, in fact, associated with an enhanced placental and fetal acetoacetate decarboxylase activity. We propose that acetone formation by the fetus could be a mechanism for pH maintenance and that acetoacetate decarboxylase can play a significant role in the handling of 4C-ketone bodies under conditions in which the substrate concentration cannot easily be controlled by other physiological mechanisms.

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