Ketone bodies inhibit leucine degradation in chick skeletal muscle > 1920-1999

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1920-1999

Ketone bodies inhibit leucine degradation in chick skeletal muscle

작성자 채식영양
작성일 87-01-01 00:00 | 조회 0 | 댓글 0

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G. Wu and JR. Thompson (1987). Ketone bodies inhibit leucine degradation in chick skeletal muscle. The International journal of biochemistry, 19(10), 937-43. https://doi.org/10.1016/0020-711x(87)90175-3

PubMed 3666283


[Abstract]
1. DL-beta-hydroxybutyrate (4 mM) increased the net rate of leucine transamination and the net rate of 2-oxoisocaproate (KIC) production in extensor digitorum communis muscles from fed chicks. 2. DL-beta-hydroxybutyrate at 1 and 4 mM inhibited leucine oxidative decarboxylation in muscles from fed chicks. 3. Acetoacetate at 1 and 4 mM inhibited leucine oxidative decarboxylation and total leucine oxidation, but increased net KIC production in muscles from fed chicks. 4. Both DL-beta-hydroxybutyrate and acetoacetate at 1 and 4 mM inhibited the net rate of leucine transamination and the rates of leucine oxidative decarboxylation and total leucine oxidation in muscles from 24-hr fasted chicks.

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1920-1999 목록
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