X. Fang, Q. Zhang and H. Yang (2024). Observation on the Therapeutic Safety of Pulsatile Intravenous Insulin Therapy Combined with Critical Value Early Warning Nursing for Diabetic Ketoacidosis Patients. Alternative therapies in health and medicine, 30(4), 71-75.

PubMed 37883775

[Abstract]
OBJECTIVE: To observe the therapeutic effect of pulsatile intravenous insulin therapy (PIVIT) combined with critical value early warning nursing on diabetic ketoacidosis (DKA).

METHODS: Ninety-six DKA patients treated in our hospital between May 2021 and February 2023 were selected as the research subjects, of which 53 cases received PIVIT (research group) and the other 43 cases received insulin intravenous infusion therapy (control group). The blood glucose (BG), condition, pH control time and the incidence of adverse reactions were analyzed in the two groups. Changes in pre- and post-treatment BG, cardiac function, β-Hydroxybutyric acid (β-HBA), lactate (Lac), and blood ketone body (BKB) were determined before and after treatment. In addition, patients' psychological status was assessed using the Self-rating Depression/Anxiety Scale (SDS/SAS) and their satisfaction with the nursing services was investigated.

RESULTS: The research group took less time to control BG, condition, and pH value than control group, with lower BG, β-HBA, Lac, and BKB levels and better cardiac function after treatment (P < .05). No notable differences were identified between groups in terms of adverse reactions, SAS and SDS scores, and nursing satisfaction (P > .05).

CONCLUSIONS: PIVIT combined with critical value early warning nursing can alleviate the acidosis of DKA patients more quickly and effectively.