R. Horikoshi, T. Kitamura and K. Miyaji (2019). Ketoacidosis related to sodium glucose cotransporter 2 inhibitors after emergency coronary surgery. Interactive cardiovascular and thoracic surgery, 29(2), 323–324. https://doi.org/10.1093/icvts/ivz091

PubMed 30968118

[Abstract]
Sodium glucose cotransporter 2 inhibitors are currently widely used antihyperglycaemic medications that are considered to be associated with euglycaemic diabetic ketoacidosis. We report 2 cases of patients who received sodium glucose cotransporter 2 inhibitors until emergency coronary artery bypass grafting (CABG) and developed euglycaemic ketoacidosis after surgery; they were treated with sugar replenishment and insulin infusion. In one case, coronary angiography revealed a spastic change of the bypass graft possibly due to severe acidosis. A rapid diagnosis and proper intervention are crucial to achieve better outcomes with CABG.