M. Baalaaji, M. Jayashree, K. Nallasamy, S. Singhi and A. Bansal (2018). Predictors and Outcome of Acute Kidney Injury in Children with Diabetic Ketoacidosis. Indian pediatrics, 55(4), 311-314.

PubMed 29428918

[Abstract]
OBJECTIVE: To identify predictors and outcome of acute kidney injury (AKI) in children with diabetic ketoacidosis (DKA) admitted to a Pediatric Intensive Care Unit (PICU).

METHODS: Retrospective case review of 79 children with DKA admitted between 2011-2014.

RESULTS: Twenty eight children developed AKI during the hospital stay; 20 (71.4%) recovered with hydration alone. Serum chloride at 24 hours was independently associated with AKI. Children with AKI had prolonged acidosis and PICU stay and higher mortality.

CONCLUSION: Majority of children with AKI and DKA, recover with hydration. Hyperchloremia at 24 hours had independent association with AKI, although cause-effect relation could not be ascertained.