A bioelectronic system for insulin release triggered by ketone body mi…
작성자 채식영양
작성일 15-01-01 00:00
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M. Gamella, N. Guz, JM. Pingarrón, R. Aslebagh, CC. Darie and E. Katz (2015). A bioelectronic system for insulin release triggered by ketone body mimicking diabetic ketoacidosis in vitro. Chemical communications (Cambridge, England), 51(36), 7618-21. https://doi.org/10.1039/c5cc01498k
[Abstract]
A bioelectronic system composed of two modified electrodes, one activated in the presence of ketone bodies, a biomarker of diabetic ketoacidosis, and another releasing insulin upon receiving a signal, was designed and tested in vitro to operate as a Sense-and-Act device. The functional integration of biomarker-sensing and insulin-releasing electrodes represents a step to a theranostic system with autonomous operation.
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