O. Pirgon, ME. Atabek and A. Sert (2009). Diabetic ketoacidosis, thyroiditis and alopecia areata in a child with Down syndrome. Indian journal of pediatrics, 76(12), 1263-4. https://doi.org/10.1007/s12098-009-0242-7

PubMed 20012788

[Abstract]
A 10-year-old girl with Down syndrome and alopecia areata was admitted with severe ketoacidosis. She had high blood glucose level: 615 mg/dL and her HbAlc level was 13.3 %. After the control of ketoacidosis and reduction of the plasma glucose level, we found low free T4 level and high TSH levels. Thyroid peroxidase antibodies titer was 1383 IU/mL and both gliadin and endomysial antibodies were negative. This was the first report of a child with Down syndrome showing type 1 diabetes combined with alopecia areata and autoimmune thyroid disease.